The Central Research Institute (CRI), Kasauli, is a leading research and vaccine manufacturing institute located in Himachal Pradesh, India. Established in 1905, it operates under the Directorate General of Health Services, part of the Ministry of Health and Family Welfare. The institute focuses on producing life-saving immunobiologicals, including DPT vaccines and various antisera, while also conducting surveillance and research in public health.

CRI Kasauli is equipped with specialized laboratories for diseases such as polio, influenza, and rabies. It also provides medical services, including a treatment center, clinical diagnostics, and a yellow fever vaccination center. The institute is recognized for its pioneering role in vaccine manufacturing and has achieved significant milestones, including the development of a cGMP compliant facility for vaccine production.

In addition to its research and manufacturing capabilities, CRI Kasauli offers an MSc program in Microbiology, contributing to education and training in the field. The institute aims to continue developing vaccines for emerging diseases and to serve as a hub for training in immunobiologicals.